近期一项发表于《自然·通讯》的研究表明，高纤维饮食可能在延缓癌症进展方面发挥重要作用。研究人员发现，膳食纤维在肠道中被微生物发酵后，会产生一种名为短链脂肪酸（如丁酸）的代谢物。这些物质不仅能调节免疫系统，还能抑制肿瘤微环境中的炎症反应，从而减缓某些类型癌症（如结肠癌、乳腺癌）的发展速度。实验显示，在摄入高纤维饮食的小鼠模型中，肿瘤生长速度明显慢于低纤维组。此外，高纤维饮食还增强了免疫检查点抑制剂等免疫疗法的效果。这提示我们，日常饮食结构可能直接影响癌症治疗的成效。专家建议，成年人每日应摄入25–30克膳食纤维，来源包括全谷物、豆类、蔬菜和水果。虽然高纤维饮食不能替代正规治疗，但它可作为辅助手段，帮助“拖住”癌症的脚步，提升整体健康水平与治疗响应率。
A recent study published in Nature Communications suggests that a high-fiber diet may play a significant role in slowing cancer progression. Researchers found that when dietary fiber is fermented by gut microbes, it produces metabolites known as short-chain fatty acids (such as butyrate). These compounds not only modulate the immune system but also suppress inflammatory responses within the tumor microenvironment, thereby decelerating the development of certain cancers—including colorectal and breast cancer.In mouse models, tumors grew significantly slower in animals fed a high-fiber diet compared to those on a low-fiber regimen. Moreover, the high-fiber diet enhanced the effectiveness of immunotherapies like immune checkpoint inhibitors, indicating that everyday dietary choices may directly influence cancer treatment outcomes.Experts recommend that adults consume 25–30 grams of dietary fiber daily from sources such as whole grains, legumes, vegetables, and fruits. While a high-fiber diet cannot replace standard cancer treatments, it may serve as a supportive strategy to help ‘hold back’ cancer progression and improve overall health and therapeutic response.
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